Merz Aesthetics Celebrates 15 Years of XEOMIN® (incobotulinumtoxinA) in the U.S. with One Year of Free Treatments Sweepstakes & New Campaign

With 43+ Million Vials Shipped Globally¹, XEOMIN^® continues to be a leader in the toxin industry

RALEIGH, N.C.–(BUSINESS WIRE)–Merz Aesthetics, the world’s largest dedicated medical aesthetics business, celebrates 15 years since its flagship brand XEOMIN^® was first approved for aesthetic use by the U.S. Food and Drug Administration (FDA). XEOMIN^® is a double-purified neurotoxin, FDA approved for the simultaneous treatment of upper facial lines – forehead lines, frown lines and crow’s feet. To celebrate this 15-year U.S. milestone, 15 lucky winners will receive a year of free XEOMIN^® treatments through Xperience+ by Merz Aesthetics U.S. patient loyalty program.

In addition, Merz Aesthetics is also launching a new, refreshed campaign for XEOMIN^® in celebration of the milestone. The new multi-channel initiative—spanning digital platforms to in-office touchpoints—aims to empower patients to ask for XEOMIN^® by showcasing XEOMIN^®’s natural-looking results that allow people to express themselves.

Containing only three ingredients, XEOMIN^® is the first and only double-purified treatment with XTRACT Technology^®, clinically proven to smooth upper facial lines for natural-looking results¹. XEOMIN^® has a 96% patient satisfaction rate^2,3 and a clinically proven track record of delivering safe, effective, and consistent results.^2,4,5

“Since its debut, XEOMIN^® has been a trusted choice for patients and providers seeking effective, natural-looking results,” said Patrick Urban, President, North America, Merz Aesthetics. “Celebrating 15 years is more than a milestone—it’s a testament to our unwavering commitment to proven performance and advancing aesthetic care.”

With XEOMIN^®, no patients in pivotal clinical studies developed treatment resistance due to neutralizing antibodies. In fact, unnecessary proteins found in some other toxin formulations on the U.S. market may cause an immune response which can lead to a decreased effect and failure of treatment.⁶ In a recent survey, just over 1 in 3 toxin users reported to have experienced decreased, or lessening effects, of toxin treatments.⁷ XEOMIN^®’s formulation minimizes this risk and offers a consistent experience, treatment after treatment.

“Leveraging our proprietary XTRACT Technology^® manufacturing process, we have established ourselves as a pioneer in neurotoxins, delivering outcomes and efficacy that both patients and providers expect,” said Dr. Samantha Kerr, Chief Scientific Officer, Merz Aesthetics. “We’re committed to driving continued innovation for years to come.”

To celebrate this U.S. milestone, XEOMIN^® is giving 15 lucky U.S. patients the opportunity to win a free year of XEOMIN^® treatments through Xperience+ by Merz Aesthetics with a participating Xperience+ provider. From February 11 to March 11, 2026, patients are invited to enter HERE and create an account or login to Xperience+ at xperiencemerz.com. No purchase necessary. Full terms and conditions are included in the entry form.

To learn more about XEOMIN^® and locate a local provider, visit XeominAesthetic.com to access the Find a Provider tool. Or sign up for Xperience+ at xperiencemerz.com to receive instant and future rewards on XEOMIN^® and additional Merz Aesthetics treatments.

Keep up with XEOMIN^® on Instagram @XeominAesthetic.

References

1. Merz Data on File 2025; Combined Merz Aesthetics and Merz Therapeutics.
2. Kane MA, et al. Dermatol Surg. 2015;41(11):1319.
3. Prager W. et al. Clin Cosmet Investig Dermatol. 2012;5: 53-58.
4. Fischer T, et al. JDD. 2020;19(5):461-469.
5. Rzany B, et al. Dermatol Surg. 2013 Jan;39(1):95-103.
6. Hefter et al. Ther Adv Neurol Disord. 2019 Dec 16;12:1756286419892078.
7. Merz Data on File 2023.

About Merz Aesthetics

Merz Aesthetics is a medical aesthetics business with a long history of empowering health care professionals, patients and employees to live every day with confidence. We aim to help people around the world look, feel and live like the best versions of themselves — however they define it. Clinically proven, its product portfolio includes injectables, devices and skin care treatments designed to meet each patient’s needs with high standards of safety and efficacy. Being family owned for more than 115 years, Merz Aesthetics is known for building unique connections with customers who feel like family. Merz Aesthetics^®’ global headquarters is in Raleigh, N.C., with a commercial presence in 90 countries worldwide. It is also a part of Merz Group, which was founded in 1908 and is based in Frankfurt, Germany. Learn more at us.merzaesthetics.com.

About XEOMIN^® (incobotulinumtoxinA)

XEOMIN^® (incobotulinumtoxinA) is a botulinum toxin type A approved by the U.S. Food and Drug Administration (FDA) for the simultaneous treatment of upper facial lines – forehead lines, frown lines and crow’s feet. XEOMIN^® is indicated to temporarily improve the look of moderate to severe upper facial lines. For more information, including Full Prescribing Information and Medication Guide, please visit www.xeominaesthetic.com. See below for Important Consumer Safety Information.

Head-to-head studies evaluating the relative risk of immunogenicity due to the presence or absence of complexing/unnecessary proteins have not been performed.

XEOMIN^® (incobotulinumtoxinA) IMPORTANT CONSUMER SAFETY INFORMATION

Read the Medication Guide before you start receiving XEOMIN (Zeo-min) and each time XEOMIN is given to you as there may be new information. The risk information provided here is not comprehensive.

To learn more:

• Talk to your health care provider or pharmacist
• Visit www.xeominaesthetic.com to obtain the Full Prescribing Information and Medication Guide
• Call 1-866-862-1211

Uses: XEOMIN is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe upper facial lines (frown lines, forehead lines, and crow’s feet) in adults for a short period of time (temporary). Please see additional Important Safety Information below and Full Prescribing Information and Medication Guide at XeominAesthetic.com.

Warnings: XEOMIN may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems anytime (hours to weeks) after treatment with XEOMIN:

• Problems with swallowing, speaking, or breathing can happen within hours to weeks after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with XEOMIN.
  • People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN.
  • Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems.
• Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.

These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities.

Do not use XEOMIN if you are allergic to XEOMIN or any of the ingredients in XEOMIN (see the end of this Guide for a list of ingredients in XEOMIN), had an allergic reaction to any other botulinum toxin products such as rimabotulinumtoxinB (MYOBLOC^®), onabotulinumtoxinA (BOTOX^®, BOTOX^® COSMETIC), or abobotulinumtoxinA (DYSPORT^®) or have a skin infection at the planned injection site.

Before receiving XEOMIN, tell your doctor about all of your medical conditions, including if you:

• have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis or Lambert-Eaton syndrome)
• have had any side effect from any other botulinum toxin in the past
• have a breathing problem such as asthma or emphysema
• have a history of swallowing problems or inhaling food or fluid into your lungs (aspiration)
• have bleeding problems
• have drooping eyelids
• have plans to have surgery
• have had surgery on your face
• are pregnant or plan to become pregnant. It is not known if XEOMIN can harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if XEOMIN passes into breast milk.

Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Talk to your doctor before you take any new medicines after you receive XEOMIN.

Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past. Especially tell your doctor if you

• have received any other botulinum toxin product in the last four months
• have received injections of botulinum toxin such as rimabotulinumtoxinB (MYOBLOC^®), onabotulinumtoxinA (BOTOX^®, BOTOX^® COSMETIC) and abobotulinumtoxinA (DYSPORT^®) in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN may be different from other botulinum toxin products that you have received.
• have recently received an antibiotic by injection
• take muscle relaxants
• take an allergy or cold medicine
• take a sleep medicine

Ask your doctor if you are not sure if your medicine is one that is listed above. Know the medicines you take. Keep a list of your medicines with you to show your doctor and pharmacist each time you get a new medicine.

Possible Side Effects

XEOMIN can cause serious side effects that can be life threatening including allergic reactions. Symptoms of an allergic reaction to XEOMIN may include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or asthma symptoms, or if you get dizzy or faint. See “Warnings.”

The most common side effect of XEOMIN in people with upper facial lines include:

• injection site bruising

These are not all the possible side effects of XEOMIN. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch or call 1-800-FDA-1088.

General information about the safe and effective use of XEOMIN

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. You can ask your pharmacist or doctor for information about XEOMIN that is written for health professionals.

Active Ingredient: botulinum toxin type A

Inactive Ingredients: human albumin and sucrose

Copyright © 2026 Merz North America, Inc. All rights reserved

Contacts

Dan Strickford

Senior Director, U.S. Brand Communications, Merz Aesthetics

[email protected]

Janell Vanarthos

Vice President, DeVries Global

[email protected]