Press Release

LifeCanvas Launches Open-Top Light Sheet Microscope for Streamlined 3D Imaging

DALISPIM combines unmatched sample compatibility with high-resolution, high-speed imaging for easily automatable workflows


CAMBRIDGE, Mass.–(BUSINESS WIRE)–#Bioimaging–LifeCanvas Technologies introduces DALISPIM, a new open-top light sheet microscope that redefines high-throughput spatial biology. With patent-pending Depth Adaptive Light Interface (DALI) technology, its unique design enables seamless imaging of tissues in standard sample carriers like multiwell plates. DALISPIM marks a new era in 3D bioimaging for drug and disease model screening.

Effortless imaging of diverse sample and tissue types

Combining the broad compatibility of an inverted microscope with high-speed, high-resolution volumetric imaging, DALISPIM enables direct examination of tissues in standard carriers like well plates, Petri dishes, slide glasses, and organ-on-a-chip devices. DALISPIM facilitates imaging multiplexed experiments, and is compatible with follow-up confocal microscopy for higher-resolution data capture.

Experience light sheet microscopy, optimized

  • Unmatched versatility: DALI technology enables aberration-free volumetric imaging of plated samples up to 6-8mm without immersion baths. Easily investigate intact organs, organoids, biopsies, tissue sections, model organisms, and more.
  • High speed, high resolution: DALISPIM leverages patented axial sweeping technology (Dean et al. 2015) to rapidly generate images with uniformly high resolution across the entire field of view.
  • Simple, intuitive acquisition: With easy-to-use software and step-by-step instructions for alignment and tiling setup, you can readily set up boundary parameters, optimize acquisition settings, and navigate through samples.
  • End-to-end solutions and support: A complete post-processing package takes you from acquisition to 3D volumetric datasets. In addition to their intact sample processing pipeline, LifeCanvas also offers MOSAIC: a high-performance networked data storage solution designed for light sheet datasets.

Learn more about DALISPIM and get in touch with imaging experts on the LifeCanvas website.

About LifeCanvas Technologies

LifeCanvas is a biotech company building pioneering technologies in volumetric tissue processing, light sheet imaging, and data analysis. By empowering researchers with next-generation tools and services for comprehensive molecular mapping, LifeCanvas is expediting drug discovery and development, disease model phenotyping, and basic research. Get the latest news on the LifeCanvas website and LinkedIn.

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Media contact
Adrian Golumbeanu

[email protected]

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