Press Release

InterAx and Alveus Announce Strategic Research and Licensing Agreement to Develop Differentiated Therapeutic Candidate for Metabolic Disease

ZURICH & PHILADELPHIA & COPENHAGEN, Denmark–(BUSINESS WIRE)–#BiotechnologyInterAx Biotech Ltd (โ€œInterAxโ€) and Alveus Therapeutics Inc. (โ€œAlveusโ€) today announced a strategic research collaboration and licensing agreement to develop a differentiated small molecule candidate for metabolic disease to deliver durable weight loss with superior tolerability.


This partnership forms a joint research effort on a target and modality of established but untapped therapeutic interest by combining InterAxโ€™s Deep Signalโ„ข discovery platform โ€“ designed to optimize candidates toward superior signaling profiles โ€“ with Alveusโ€™s deep R&D expertise and leadership in obesity, diabetes, and cardiometabolic disease. While financial terms remain undisclosed, the agreement includes an upfront payment and eligibility for future development, regulatory, and commercial milestones.

โ€œWe are thrilled to join forces with Alveus to advance a highly differentiated therapeutic candidate designed to overcome the limitations of todayโ€™s obesity medications,โ€ said Andrew Roberts, CEO of InterAx. โ€œOur Deep Signalโ„ข platform is specifically designed to navigate the complexity of GPCR signaling, and Alveusโ€™s deep metabolic expertise makes them the ideal partner to bring this therapeutic candidate to patients.โ€

โ€œInterAxโ€™s unique platform integrates drug chemistry, protein structure, cellular signaling and therapeutic efficacy โ€“ the essential expertise for effectively and efficiently designing highly differentiated candidates. We are excited to apply this unique approach to our joint program efforts,โ€ said Jacob Jeppesen, Chief Scientific Officer and Head of R&D at Alveus.

InterAx Biotech Ltd

InterAx is a Swiss Biotech company redefining drug discovery by understanding the impact of treatments on diseases before pre-clinical trials begin โ€“ an analysis traditionally inaccessible to very early programs. Focusing on GPCR small molecules, the Deep Signalโ„ข platform deciphers complex biology by uncovering disease mechanisms at the cellular signaling level. This approach starts with advanced methods centered on drug chemistry and receptor structure, and then moves beyond them โ€“ into cell signaling โ€“ enabling unrivaled optimization that delivers differentiated drug candidates with higher efficacy, enhanced safety, and lower clinical failure rates.

InterAxโ€™s three-asset portfolio demonstrates this impact, including a biologically differentiated GLP-1 asset that addresses the challenges seen with small-molecule competitors, a partnered metabolic program, as well as an innovative ACKR3 immuno-oncology program driven by unique target understanding. With four additional targets identified where the platform provides a strong edge, the company is poised to expand into neurologic and autoimmune indications.

For more information, please visit linkedin.com/company/interax-biotech | www.interaxbiotech.com.

About Alveus Therapeutics

Alveus Therapeutics is a clinical-stage biotechnology company developing next-generation therapies for obesity and metabolic diseases, designed for sustained efficacy, improved tolerability, and reduced treatment burden.

Alveus is headquartered in Philadelphia, PA, with research and development operations based in Copenhagen, Denmark.

For more information, please visit www.alveustx.com.

Contacts

InterAx Biotech Ltd

Media contact: Luca Zenone, [email protected]

Investor & Media Contacts
Alveus Therapeutics
Media
Sasha Damouni Ellis, Damouni Group LLC

[email protected]
Investors
Victoria Igumnova, Meru Advisors LLC

[email protected]

Author

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