Heart Rhythm Case Reports Publishes Notable Case Detailing First Use of AI-Guided ECG Mapping for Left Bundle Branch Area Pacing

Case Report Demonstrates How vMap Enhances Accuracy and Reduces Risk in Pacemaker Implantation

SAN DIEGO–(BUSINESS WIRE)–#HRX2024—Vektor Medical, a leader in non-invasive, AI-powered arrhythmia analysis technology, today announced the publication of a groundbreaking case in Heart Rhythm Case Reports. Conducted by physicians from the University of California San Diego (UCSD), the case details the first successful use of AI-enabled ECG mapping to guide left bundle branch area pacing (LBBAP) implantation. Findings highlight how vMap, a non-invasive AI-powered mapping technology, enhances procedural efficiency, accuracy, and patient safety during LBBAP lead positioning.

As LBBAP becomes a preferred physiologic pacing technique, vMap has the potential to offer a transformative approach by reducing fluoroscopy exposure and eliminating the need for contrast agents – critical factors in enhancing patient safety and procedural outcomes.

The patient in the case report, a 90-year-old male with advanced chronic kidney disease and a severe iodinated contrast allergy, underwent a dual-chamber LBBAP implantation as physicians used vMap for peri-procedural AI-driven guidance. The procedure was completed successfully with minimized fluoroscopy time and without contrast injection, mitigating risks associated with traditional approaches for the patient and physician.

Procedure Highlights:

• vMap provided peri-procedural, AI-driven guidance to position the lead accurately on the RV septum.
• vMap compared the patient’s QRS morphology with a digital reference library of thousands of cardiac simulations of right ventricular pacing, helping localize the lead tip within the heart.
• Successful lead placement was achieved with confirmed left bundle capture, reducing reliance on traditional fluoroscopic imaging.
• vMap’s ability to store and analyze paced QRS morphology enabled more efficient mapping, particularly in cases where the ideal pacing site was not immediately encountered.

“This case report illustrates how AI-driven ECG mapping can be seamlessly integrated into LBBAP procedures, enhancing accuracy while reducing procedural risks,” said Dr. Ulrika Birgersdotter-Green, Director of Pacemaker and ICD Services at UC San Diego Health and a case report co-author. “By leveraging vMap’s advanced mapping capabilities, we can improve implantation accuracy and safety, particularly for high-risk patients.”

The case report underscores vMap’s ability to transform cardiac pacing workflows while prioritizing patient safety. As the only FDA-cleared, non-invasive AI-based solution for mapping arrhythmias and analyzing atrial and ventricular pacing via a standard 12-lead ECG, vMap represents a significant advancement in electrophysiology.

“This case is the first time vMap has been used to help guide LBBAP implantation. In addition to the positive procedural benefits, it’s a very clear demonstration of the potential for vMap to more broadly improve cardiac care and advance various cardiac interventions,” said Rob Krummen, CEO of Vektor Medical.

For more information on Vektor Medical and vMap, visit www.vektormedical.com and connect on LinkedIn and X.

About Vektor Medical

Headquartered in San Diego, Vektor Medical is on a mission to revolutionize arrhythmia care for millions affected by atrial fibrillation and other arrhythmias. Through its AI-powered, non-invasive arrhythmia analysis technology, vMap, the company aims to improve cardiac ablation outcomes, optimize workflows, and increase procedural efficiency. For more information about vMap and Vektor Medical, please visit www.vektormedical.com.

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