Translating decades of clinical neuroscience research into next-generation AI—ALLT.AI harnesses key data from damaged brains to create radically more efficient LLMs while advancing treatment for neurological language disorders
COLUMBIA, S.C., Sept. 17, 2025 /PRNewswire/ — NXTLLM and MKHSTRY Labs today announced the formation of ALLT.AI, a joint venture introducing BLUM (Brain-LLM Unified Model), a patented technology that translates language recovery patterns from stroke patients into AI architectures that reduce computational requirements by orders of magnitude.
By studying how damaged brains achieve remarkable language recovery despite losing significant brain tissue, ALLT.AI has identified which neural pathways are truly essential for language processing, insights that promise to transform both AI economics and treatment for neurological language disorders.
While today’s large language models consume enough electricity to power entire neighborhoods just to write basic text, the human brain – nature’s original language processor – can run for three days on the energy in a single AA battery. BLUM bridges this staggering efficiency gap by applying a counterintuitive principle: damaged brains reveal optimization secrets that healthy brains cannot. When stroke damages specific brain regions, the resulting language impairments show precisely which components are critical versus redundant. This is a natural experiment that ALLT.AI now replicates in artificial systems.
The venture is led by Dr. Julius Fridriksson, CEO of ALLT.AI and Vice President of Research at the University of South Carolina, whose pioneering research has advanced the field of aphasia recovery through detailed mapping of how the brain reorganizes after injury. A world-renowned expert in aphasia – the devastating loss of language ability affecting over 2 million Americans after stroke – Fridriksson has spent decades documenting how some patients achieve remarkable recovery despite extensive brain damage. With over 250 scientific publications focused on the neurobiology of human language and the neural mechanisms of aphasia recovery, his research has compiled unprecedented data from thousands of stroke patients, creating the foundation for ALLT.AI’s revolutionary approach to AI efficiency.
“The brain remains the ultimate LLM – faster, more efficient, and far more intuitive than anything we’ve built artificially,” said Fridriksson. “Every word ever spoken, every child’s first sentence, every line Shakespeare wrote emerged from this remarkable organ. Current AI has diverged from neuroscience, pursuing infinite scale with diminishing returns. We’re bringing AI back to its biological roots, but through the lens of brain damage and recovery – the most powerful way to understand what’s truly necessary for language processing.”
BLUM utilizes a translation algorithm that maps impaired language output from “lesioned” LLMs to probabilistic brain lesion patterns observed in neuroimaging models of the human brain. The technology has already demonstrated the ability to simulate specific types of aphasia in artificial systems, and early research shows promise for modeling other neurological conditions, including the language symptoms of Alzheimer’s disease and various forms of dementia. These validated models reveal which LLM components can be eliminated or reduced while maintaining performance, providing AI developers with a scientifically proven pathway to achieve comparable results with a fraction of current computational requirements.
Jeff Charney, founder of MKHSTRY and President of ALLT.AI, sees transformative commercial potential in the technology. “This partnership proves that brain-inspired architectures don’t just improve language models; they redefine them,” said Charney. “We’re looking to engage with leading AI companies who recognize that the next breakthrough isn’t about adding more parameters, but fundamentally rethinking efficiency. The company that moves first on BLUM won’t just win with reduced costs; they’ll help pioneer the shift from brute-force computing to brain-inspired intelligence. In a world racing to make LLMs more powerful at any cost, ALLT.AI provides a scientifically proven path that opens the door to healthier people and a healthier planet.”
The innovation delivers a compelling dual benefit: every efficiency breakthrough for AI partners advances understanding and treatment for millions suffering from aphasia and potentially other neurological conditions such as Alzheimer’s disease. “We’re not competing with large AI companies; we’re offering them a way to dramatically reduce computational costs while our clinical insights grow with every implementation,” Fridriksson explained. “It’s the ultimate win-win: radical efficiency for AI and new hope for those waiting to reclaim their voices through more personalized, effective treatments.”
With its formation, ALLT.AI is actively seeking strategic partnerships with major AI companies to integrate BLUM’s breakthrough neuroscience into their LLM development pipelines. With patented technology validated on thousands of patients and set for release in late 2025, BLUM represents the first scientifically proven method to achieve order-of-magnitude efficiency gains by applying biological principles of brain damage and recovery to artificial systems. As the AI industry evolves beyond pure computational scaling, early partners can shape the next generation of brain-inspired architectures while contributing to groundbreaking medical research.
For partnership inquiries, contact: [email protected]
To schedule interviews with Dr. Julius Fridriksson or Jeff Charney please call Dr. Roger Newman-Norlund at 803-530-6793 or email him at [email protected]
About NXTLLM, LLC NXTLLM bridges neurobiological language models with LLMs to revolutionize AI efficiency and aphasia understanding. The company holds issued patents for core BLUM technology.
About MKHSTRY, LLC MKHSTRY is a Cleveland-based innovation collective that partners with visionary brands to disrupt the status quo through human intelligence, AI integration, and emerging technology partnerships.
View original content to download multimedia:https://www.prnewswire.com/news-releases/alltai-unveils-the-next-generation-of-large-language-models-llms-driven-by-the-remarkable-power-and-efficiency-of-the-human-brain-302558086.html
SOURCE ALLT.AI
